LAUSR

Dear Editor, Reflectance confocal microscopy (RCM) is a noninvasive diagnostic tool with near‐histologic resolution and high diagnostic accuracy. Most lesions are easily evaluated with a wide‐probe RCM; however, assessment of large lesions, scars, ill‐shaped lesions, and specific non‐flat anatomical areas (e.g., nose, ear, genitals, and periocular) might be challenging. In these scenarios handheld RCM is typically used, however, orientation is critical, and delineation is challenging. Margin mapping, for example, requires an exact one‐to‐one correlation with RCM findings. Also, the biopsy for genetic material, or aiming the most representative area of a lesion for ex vivo histopathological analysis requires visual reference. To overcome this, paper rings, paper tapes, metallic grids, plastic laminate sheet adapters, and metallic ink pens have been used, with some limitations (Table 1). Specifically, metallic ink pen tends to smear with the motion of the probe as the immersion oil used for imaging dissolves the lipophilic ink.