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CAQ Corner: The practical assessment and management of sarcopenia, frailty, and malnutrition in patients with cirrhosis

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In recent years, our understanding of the impact of sarcopenia, frailty, and malnutrition in cirrhosis has greatly expanded. All three of these conditions have been associated with increased waitlist mortality… Click to show full abstract

In recent years, our understanding of the impact of sarcopenia, frailty, and malnutrition in cirrhosis has greatly expanded. All three of these conditions have been associated with increased waitlist mortality beyond the Model for End‐Stage Liver Disease (MELD) score alone.[1–3] In addition, they have been shown to predict the risk of hospitalization, disability, and cirrhosis progression as well as post–liver transplantation (LT) survival.[4] As a result of these associated consequences, current guidelines now recommend the routine screening of sarcopenia, frailty, and malnutrition in all patients with cirrhosis.[5–7] This review will summarize the current standardized tools used for the evaluation of sarcopenia, frailty, and malnutrition and how to apply these constructs in the care of patients with cirrhosis.

Keywords: frailty malnutrition; patients cirrhosis; sarcopenia frailty

Journal Title: Liver Transplantation
Year Published: 2022

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