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Renal dysfunction after liver transplantation for polycystic liver disease

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To the editor, Polycystic liver disease (PLD) encompasses a group of liver disorders with varying renal involvement.[1] There are no curative treatment options and patients can require liver transplantation (LT),… Click to show full abstract

To the editor, Polycystic liver disease (PLD) encompasses a group of liver disorders with varying renal involvement.[1] There are no curative treatment options and patients can require liver transplantation (LT), as either isolated LT or simultaneous liver and kidney (SLK) transplantation in chronic kidney disease (CKD). Although patient and graft survival after LT are excellent,[2] there are reports of deteriorating renal function following isolated LT, which result in endstage renal disease (ESRD) and kidney transplantation (KT).[3] Patient numbers are small with limited details on individual risk factors and timing following LT, so realworld implications for patients and clinicians remain unclear. We sought to describe rates of renal replacement therapy (RRT) and deterioration in renal function after isolated LT for PLD.

Keywords: polycystic liver; liver; transplantation; liver disease; liver transplantation

Journal Title: Liver Transplantation
Year Published: 2022

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