LAUSR

Atom transfer radical polymerization of allyl methacrylate followed by a thiol-ene click reaction with 1-thio-β-D-glucose tetraacetate is performed to afford a new type of glycopolymers via deacetylation. Their interactions with a sugar-binding protein are evaluated by electrophoretic deposition (EPD) procedures as well as fluorescence measurements. The deposition amount of concanavalin A (conA) in the presence of glucose or galactose measured by EPD is remarkably different from that in the presence of the synthesized glycopolymer, even though the concentration of sugar residue is the same. The deposition amount, as well as the electric current that flows during the EPD, is higher in the presence of the polymer, which confirms that interaction of conA with the glycopolymer is detected by the EPD procedure.