LAUSR

The photochemical reaction is a very important type of chemical reactions. Visualizing and controlling photo-mediated reactions is a long-standing goal and challenge. In this regard, single-molecule electrical detection with label-free, real-time and in situ characteristics has unique advantages in monitoring the dynamic process of photoreactions at the single-molecule level. In this Review, we provide a valuable summary of the latest process of single-molecule photochemical reactions based on single-molecule electrical platforms. The single-molecule electrical detection platforms for monitoring photoreactions are displayed, including their fundamental principles, construction methods and practical applications. The single-molecule studies of two different types of light-mediated reactions are summarized as below: i) photo-induced reactions, including reversible cyclization, conformational isomerization and other photo-related reactions; ii) plasmon-mediated photoreactions, including reaction mechanisms and concrete examples, such as plasmon-induced photolysis of S-S/O-O bonds and tautomerization of porphycene. In addition, the prospects for future research directions and challenges in this field are also discussed. This article is protected by copyright. All rights reserved.