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Divergence of mutational signatures in association with breast cancer subtype

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Abnormal molecular processes occurring throughout the genome leave distinct somatic mutational patterns termed mutational signatures. Exploring the associations between mutational signatures and clinicopathological features can unravel potential mechanisms driving tumorigenic… Click to show full abstract

Abnormal molecular processes occurring throughout the genome leave distinct somatic mutational patterns termed mutational signatures. Exploring the associations between mutational signatures and clinicopathological features can unravel potential mechanisms driving tumorigenic processes.

Keywords: cancer subtype; signatures association; divergence mutational; breast cancer; mutational signatures; association breast

Journal Title: Molecular Carcinogenesis
Year Published: 2022

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