LAUSR

Within movement disorders occurring during or after coronavirus 2019 (COVID-19), myoclonus was observed both isolated and in the context of encephalopathy, as well as with ataxia, but without opsoclonus. 1 However, pathomechanisms remain poorly understood. We report three adult male patients with mild symptoms of COVID-19 and subacute onset of ataxia and myoclonus arising after SARS-CoV-2 infection (Table 1), a condition recently identi fi ed as “ SARS-CoV-2 – related acute cerebellar ataxia and myoclonus ” (ACAM) syndrome. 2 Here, ACAM syndrome occurred in the context of encephalopathy and, although litera-ture reports that spontaneous recovery occurs after 2 months in almost all patients, 3 it was rapidly sensitive to intravenous immu-noglobulin (IVIg) (case 1 and 2) or plasmapheresis (PEX) (case 3). Moreover, unlike previous reports, our patients did not have structural abnormality on brain magnetic resonance imaging (MRI) or cerebrospinal fl uid (CSF) evidence of SARS-CoV-2, possibly as a result of transient or undetectable virus. 3 Overall, neurological