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Prodromal Cognitive Changes as a Prognostic Indicator of Forthcoming Huntington's Disease Severity: A Retrospective Longitudinal Study

Cognitive changes in Huntington's disease (HD) precede motor manifestations. ENROLL‐HD platform includes four cognitive measures of information processing speed (IPS). Our group is eager to seek clinical markers in the… Click to show full abstract

Cognitive changes in Huntington's disease (HD) precede motor manifestations. ENROLL‐HD platform includes four cognitive measures of information processing speed (IPS). Our group is eager to seek clinical markers in the life stage that is as close as possible to the age of onset (ie, the so called prodromal HD phase) because this is the best time for therapeutic interventions.

Keywords: prognostic indicator; huntington disease; prodromal cognitive; changes prognostic; cognitive changes

Journal Title: Movement Disorders Clinical Practice
Year Published: 2024

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