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Background and Objective: Mitochondrial dysfunction has been implicated in several neurodegenerative diseases. Creatine administration increases concentration of the energy buffer phosphocreatine, exerting protective effects in the brain. We evaluate whether… Click to show full abstract
Background and Objective: Mitochondrial dysfunction has been implicated in several neurodegenerative diseases. Creatine administration increases concentration of the energy buffer phosphocreatine, exerting protective effects in the brain. We evaluate whether a creatine‐enriched diet would be beneficial for a mouse model of spinocerebellar ataxia type 3, a genetically defined neurodegenerative disease for which no treatment is available.
Keywords:
model spinocerebellar;
ataxia type;
spinocerebellar ataxia;
mouse model
Journal Title: Movement Disorders
Year Published: 2018
Link to full text (if available)
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Journal Title: Movement Disorders
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!