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Identifying the Functional Brain Network of Motor Reserve in Early Parkinson's Disease

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The severity of motor symptoms in Parkinson's disease (PD) does not always correlate with the degree of nigral dopaminergic neuronal loss. Individuals with greater motor reserve may have milder motor… Click to show full abstract

The severity of motor symptoms in Parkinson's disease (PD) does not always correlate with the degree of nigral dopaminergic neuronal loss. Individuals with greater motor reserve may have milder motor signs than their striatal dopamine loss. In this study, we explored the functional brain network associated with motor reserve in early‐stage PD.

Keywords: reserve early; brain network; functional brain; motor; parkinson disease; motor reserve

Journal Title: Movement Disorders
Year Published: 2020

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