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In right‐handed patients with Parkinson's disease (PD) or isolated rapid eye movement sleep behavior disorder, dopamine transporter (DAT) [(123)I]β‐carboxymethyoxy‐3‐β‐(4‐iodophenyl) tropane single photon emission computed tomography (SPECT) shows predominant nigrostriatal deficit… Click to show full abstract
In right‐handed patients with Parkinson's disease (PD) or isolated rapid eye movement sleep behavior disorder, dopamine transporter (DAT) [(123)I]β‐carboxymethyoxy‐3‐β‐(4‐iodophenyl) tropane single photon emission computed tomography (SPECT) shows predominant nigrostriatal deficit in the left striatum. This suggests that in PD patients, the nigrostriatal system of the dominant hemisphere is more susceptible to disease‐related dysfunction. To confirm this hypothesis, we investigated whether the nigrostriatal function is symmetric in healthy controls and in patients with PD.
Journal Title: Movement Disorders
Year Published: 2020
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