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Role of Lysosomal Gene Variants in Modulating GBA ‐Associated Parkinson's Disease Risk

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To date, variants in the GBA gene represent the most frequent large‐effect genetic factor associated with Parkinson's disease (PD). However, the reason why individuals with the same GBA variant may… Click to show full abstract

To date, variants in the GBA gene represent the most frequent large‐effect genetic factor associated with Parkinson's disease (PD). However, the reason why individuals with the same GBA variant may or may not develop neurodegeneration and PD is still unclear.

Keywords: associated parkinson; lysosomal gene; parkinson disease; role lysosomal

Journal Title: Movement Disorders
Year Published: 2022

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