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Neurofilament Light Protein as a Potential Blood Biomarker for Huntington's Disease in Children

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Juvenile‐onset Huntington's disease (JOHD) is a rare and particularly devastating form of Huntington's disease (HD) for which clinical diagnosis is challenging and robust outcome measures are lacking. Neurofilament light protein… Click to show full abstract

Juvenile‐onset Huntington's disease (JOHD) is a rare and particularly devastating form of Huntington's disease (HD) for which clinical diagnosis is challenging and robust outcome measures are lacking. Neurofilament light protein (NfL) in plasma has emerged as a prognostic biomarker for adult‐onset HD.

Keywords: huntington; biomarker; huntington disease; neurofilament light; light protein

Journal Title: Movement Disorders
Year Published: 2022

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