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Epigenetic Clock Acceleration Is Linked to Age at Onset of Parkinson's Disease

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Aging is the strongest risk factor for Parkinson's disease (PD), which is a clinically heterogeneous movement disorder with highly variable age at onset. DNA methylation age (DNAm age) is an… Click to show full abstract

Aging is the strongest risk factor for Parkinson's disease (PD), which is a clinically heterogeneous movement disorder with highly variable age at onset. DNA methylation age (DNAm age) is an epigenetic clock that could reflect biological aging.

Keywords: age onset; parkinson disease; epigenetic clock; age

Journal Title: Movement Disorders
Year Published: 2022

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