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Rest and Digest—The Basal Role of Autophagy in Neurons and Its Relevance to Parkinson's Disease

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in the basal role of autophagy in and its regulation of mitochondrial-derived in fl ammation as part of con-trol. In Brain-derived autophagosome pro fi ling the engulfment of nucleoid-enriched mitochondrial… Click to show full abstract

in the basal role of autophagy in and its regulation of mitochondrial-derived in fl ammation as part of con-trol. In Brain-derived autophagosome pro fi ling the engulfment of nucleoid-enriched mitochondrial fragments by basal autophagy in neurons, that basal autophagy regulates a balance between synaptic maintenance, bioenergetic demands, and in fl ammation. In they uncover a key role for autophagy in synaptic and mitochondrial homeostasis and possible clues for

Keywords: autophagy neurons; role; basal role; rest digest; role autophagy; digest basal

Journal Title: Movement Disorders
Year Published: 2022

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