SNCA p.V15A was reported in five families. In vitro models showed increased aggregation and seeding activity, mitochondrial damage, and apoptosis. Mutant flies had reduced flying ability and survival. Click to show full abstract
SNCA p.V15A was reported in five families. In vitro models showed increased aggregation and seeding activity, mitochondrial damage, and apoptosis. Mutant flies had reduced flying ability and survival.
Keywords:
v15a variant;
linking synuclein;
variant linking;
study snca;
snca v15a;
functional study
Journal Title: Movement Disorders
Year Published: 2024
Link to full text (if available)
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Journal Title: Movement Disorders
Year Published: 2024
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!