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Isolated REM Sleep without Atonia Is Not Equivalent to REM Sleep Behavior Disorder in Early‐Stage Parkinson's Disease

In early‐stage Parkinson's disease (PD), rapid eye movement (REM) sleep behavior disorder (RBD) predicts poor cognitive and motor outcome. However, the baseline significance and disease evolution associated with isolated REM… Click to show full abstract

In early‐stage Parkinson's disease (PD), rapid eye movement (REM) sleep behavior disorder (RBD) predicts poor cognitive and motor outcome. However, the baseline significance and disease evolution associated with isolated REM sleep without atonia (iRWA, ie, enhanced muscle tone during 8.7% of REM sleep, but no violent behavior) are not well understood.

Keywords: rem sleep; disease; early stage; stage parkinson; behavior

Journal Title: Movement Disorders
Year Published: 2024

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