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Identification of a novel somatic mutation of POU6F2 by whole‐genome sequencing in prolactinoma

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Pituitary adenomas (PAs) are one of the most common intracranial tumors; approximately half of PAs are prolactin (PRL)‐secreting PAs (prolactinomas). The genetic alterations prevalent in prolactinomas are unknown. Click to show full abstract

Pituitary adenomas (PAs) are one of the most common intracranial tumors; approximately half of PAs are prolactin (PRL)‐secreting PAs (prolactinomas). The genetic alterations prevalent in prolactinomas are unknown.

Keywords: novel somatic; whole genome; somatic mutation; mutation pou6f2; identification novel; pou6f2 whole

Journal Title: Molecular Genetics & Genomic Medicine
Year Published: 2019

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