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A polygenic biomarker to identify patients with severe hypercholesterolemia of polygenic origin

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Severe hypercholesterolemia (HC, LDL‐C > 4.9 mmol/L) affects over 30 million people worldwide. In this study, we validated a new polygenic risk score (PRS) for LDL‐C. Click to show full abstract

Severe hypercholesterolemia (HC, LDL‐C > 4.9 mmol/L) affects over 30 million people worldwide. In this study, we validated a new polygenic risk score (PRS) for LDL‐C.

Keywords: patients severe; hypercholesterolemia; polygenic biomarker; biomarker identify; identify patients; severe hypercholesterolemia

Journal Title: Molecular Genetics & Genomic Medicine
Year Published: 2020

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