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Somatic TEK variant with intraarticular venous malformation and knee hemarthrosis treated with rapamycin

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Venous malformations (VMs) are the most common vascular anomalies and have been associated with somatic variants in TEK. Current treatment of VM joint component might be challenging due to the… Click to show full abstract

Venous malformations (VMs) are the most common vascular anomalies and have been associated with somatic variants in TEK. Current treatment of VM joint component might be challenging due to the size or location of some lesions or ineffective with recurrence of malformed veins. Targeted molecular therapies after identification of genetic defects might be an alternative.

Keywords: variant intraarticular; malformation knee; tek variant; venous malformation; somatic tek; intraarticular venous

Journal Title: Molecular Genetics & Genomic Medicine
Year Published: 2022

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