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Novel biallelic mutations in TTC29 cause asthenoteratospermia and male infertility

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Multiple morphological abnormalities of the sperm flagella (MMAF), which is characterized as asthenoteratospermia involving absent, short, bent, coiled, and/or irregular‐caliber flagella, is a rare recessive inherited disorder associated with male… Click to show full abstract

Multiple morphological abnormalities of the sperm flagella (MMAF), which is characterized as asthenoteratospermia involving absent, short, bent, coiled, and/or irregular‐caliber flagella, is a rare recessive inherited disorder associated with male infertility. To date, genetic causes of MMAF cases are not fully explored.

Keywords: novel biallelic; mutations ttc29; biallelic mutations; asthenoteratospermia; male infertility

Journal Title: Molecular Genetics & Genomic Medicine
Year Published: 2022

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