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Chinese familial central precocious puberty with hyperuricemia due to recurrent DLK1 mutation: Case report and review of the literature

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Central precocious puberty (CPP) is a precocious puberty due to premature activation of the hypothalamic–pituitary‐gonadal axis (HPG). MKRN3 defects are well‐known causes of CPP, while DLK1 mutations were recently identified… Click to show full abstract

Central precocious puberty (CPP) is a precocious puberty due to premature activation of the hypothalamic–pituitary‐gonadal axis (HPG). MKRN3 defects are well‐known causes of CPP, while DLK1 mutations were recently identified in a few patients with CPP.

Keywords: precocious puberty; central precocious; puberty; familial central; chinese familial; puberty hyperuricemia

Journal Title: Molecular Genetics & Genomic Medicine
Year Published: 2022

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