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Fragile X checklists: A meta‐analysis and development of a simplified universal clinical checklist

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Clinical checklists available have been developed to assess the risk of a positive Fragile X syndrome but they include relatively small sample sizes. Therefore, we carried out a meta‐analysis that… Click to show full abstract

Clinical checklists available have been developed to assess the risk of a positive Fragile X syndrome but they include relatively small sample sizes. Therefore, we carried out a meta‐analysis that included statistical pooling of study results to obtain accurate figures on the prevalence of clinical predictors of Fragile X syndrome among patients with intellectual disability, thereby helping health professionals to improve their referrals for Fragile X testing.

Keywords: analysis; checklists meta; fragile checklists; analysis development; development simplified; meta analysis

Journal Title: Molecular Genetics & Genomic Medicine
Year Published: 2018

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