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Estimating the age of Hb G‐Coushatta [β22(B4)Glu→Ala] mutation by haplotypes of β‐globin gene cluster in Denizli, Turkey

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Hb G‐Coushatta variant was reported from various populations’ parts of the world such as Thai, Korea, Algeria, Thailand, China, Japan and Turkey. In our study, we aimed to discuss the… Click to show full abstract

Hb G‐Coushatta variant was reported from various populations’ parts of the world such as Thai, Korea, Algeria, Thailand, China, Japan and Turkey. In our study, we aimed to discuss the possible historical relationships of the Hb G‐Coushatta mutation with the possible migration routes of the world. For this purpose, associated haplotypes were determined using polymorphic loci in the beta globin gene cluster of hemoglobin G‐Coushatta and normal populations in Denizli, Turkey.

Keywords: globin gene; coushatta; denizli turkey; gene cluster; mutation

Journal Title: Molecular Genetics & Genomic Medicine
Year Published: 2018

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