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Biallelic Mutations in the Otogelin‐Like Gene ( OTOGL ) Associated With Congenital Non‐Syndromic Sensorineural Hearing Loss in a Chinese Family

Hearing loss, characterized by significant genetic heterogeneity, is a widespread global disorder. Mutations in the OTOG and OTOGL genes have recently been implicated in non‐syndromic sensorineural hearing loss. However, the… Click to show full abstract

Hearing loss, characterized by significant genetic heterogeneity, is a widespread global disorder. Mutations in the OTOG and OTOGL genes have recently been implicated in non‐syndromic sensorineural hearing loss. However, the mutation spectrum of OTOGL and its functional relevance remain incompletely understood.

Keywords: loss; non syndromic; sensorineural hearing; hearing loss; syndromic sensorineural

Journal Title: Molecular Genetics & Genomic Medicine
Year Published: 2025

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