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Association study of genetic variations of inflammatory biomarkers with susceptibility and severity of obstructive sleep apnea

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Obstructive sleep apnea (OSA) increases health risks of cardiovascular disease and stroke. Both genetic factors and environmental exposures contribute to the occurrence of OSA. The purpose of this study was… Click to show full abstract

Obstructive sleep apnea (OSA) increases health risks of cardiovascular disease and stroke. Both genetic factors and environmental exposures contribute to the occurrence of OSA. The purpose of this study was to determine the role of four functional inflammatory single nucleotide polymorphisms (SNPs) (VWF rs1063856, IL‐6 rs1800796, TNF rs1800629, and CRP rs2794521) in the susceptibility and severity of OSA.

Keywords: obstructive sleep; inflammatory; susceptibility severity; sleep apnea

Journal Title: Molecular Genetics & Genomic Medicine
Year Published: 2019

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