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Stochastic effects of the tumor‐T cell immune model

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To investigate the effects of environmental factors on the tumor growth and the T cell growth, we establish a stochastic tumor‐immune model consisting of cytotoxic T cells and helper T… Click to show full abstract

To investigate the effects of environmental factors on the tumor growth and the T cell growth, we establish a stochastic tumor‐immune model consisting of cytotoxic T cells and helper T cells. By using the Itô formula and the strong law of large numbers, we prove the existence of globally unique positive solution and obtain the sufficient conditions of the extinction and the weak persistence of tumor cells and T cells. Moreover, according to our obtained theoretical results, we perform some numerical simulations to show that different noise intensities lead to different states of tumor cells, cytotoxic T cells and helper T cells, including extinction and weak persistence, which can be useful for the prevention and control of tumor deterioration and for explaining tumor escape phenomena of clinical medicine.

Keywords: tumor; immune model; effects tumor; stochastic effects; cell

Journal Title: Mathematical Methods in the Applied Sciences
Year Published: 2021

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