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Data-driven motion correction will replace motion-tracking devices in molecular imaging-guided radiation therapy treatment planning.

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The last decade has seen abundant literature demonstrating the advantages of hybrid imaging modalities combining morphological and molecular imaging in clinical oncology. Commercial systems merging SPECT and CT, PET and… Click to show full abstract

The last decade has seen abundant literature demonstrating the advantages of hybrid imaging modalities combining morphological and molecular imaging in clinical oncology. Commercial systems merging SPECT and CT, PET and CT or PET and MRI are now widely used in the clinic and have had significant impact on patient management. Ultimately, molecular imaging-guided radiotherapy holds the promise of improved definition of tumor target volumes. However, respiratory motion management remains one of the main challenges of this technique. This has historically been handled using motion tracking devices (MTDs) but recent advances enable one to obtain motion information from the acquired image data, thus allowing the implementation of data-driven motion correction (DMC) strategies. This article is protected by copyright. All rights reserved.

Keywords: motion; imaging guided; data driven; motion tracking; molecular imaging; tracking devices

Journal Title: Medical physics
Year Published: 2018

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