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BACKGROUND Although 4D-CBCT is valuable to provide onboard image guidance for radiotherapy of moving targets, it requires a long acquisition time to achieve sufficient image quality for target localization. To improve the utility, it is highly desirable to reduce the 4D-CBCT scanning time while maintaining high-quality images. Current motion-compensated methods are limited by slow speed and compensation errors due to the severe intra-phase under-sampling PURPOSE: : In this work, we aim to propose an alternative feature-compensated method to realize the fast 4D-CBCT with high-quality images. METHODS We proposed a feature-compensated deformable convolutional network (FeaCo-DCN) to perform inter-phase compensation in the latent feature space, which has not been explored by previous studies. In FeaCo-DCN, encoding networks extract features from each phase, and then, features of other phases are deformed to those of the target phase via deformable convolutional networks. Finally, a decoding network combines and decodes features from all phases to yield high-quality images of the target phase. The proposed FeaCo-DCN was evaluated using lung cancer patient data. RESULTS (1) FeaCo-DCN generated high-quality images with accurate and clear structures for a fast 4D-CBCT scan; (2) 4D-CBCT images reconstructed by FeaCo-DCN achieved 3D tumor localization accuracy within 2.5 mm; (3) image reconstruction is nearly real-time; and (4) FeaCo-DCN achieved superior performance by all metrics compared to the top-ranked techniques in the AAPM SPARE Challenge. CONCLUSION The proposed FeaCo-DCN is effective and efficient in reconstructing 4D-CBCT while reducing about 90% of the scanning time, which can be highly valuable for moving target localization in image-guided radiotherapy. This article is protected by copyright. All rights reserved.