Ultra‐high dose rate radiotherapy elicits a biological effect (FLASH), which has been shown to reduce toxicity while maintaining tumor control in preclinical radiobiology experiments. FLASH depends on the dose rate,… Click to show full abstract
Ultra‐high dose rate radiotherapy elicits a biological effect (FLASH), which has been shown to reduce toxicity while maintaining tumor control in preclinical radiobiology experiments. FLASH depends on the dose rate, with evidence that higher dose rates drive increased normal tissue sparing. The pattern of dose delivery also has significance for conformal proton FLASH delivered via pencil beam scanning (PBS) given its unique spatio‐temporal distribution of dose deposition.
Keywords:
rate;
radiotherapy;
proton flash;
dose rate
Journal Title: Medical Physics
Year Published: 2025
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Journal Title: Medical Physics
Year Published: 2025
Link to full text (if available)
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recommendations!