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Implementation of a novel pencil beam scanning Bragg peak FLASH technique to a commercial treatment planning system

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Ultra‐high dose rate, or FLASH, radiotherapy has shown promise in preclinical experiments of sparing healthy tissue without compromising tumor control. This “FLASH effect” can compound with dosimetric sparing of the… Click to show full abstract

Ultra‐high dose rate, or FLASH, radiotherapy has shown promise in preclinical experiments of sparing healthy tissue without compromising tumor control. This “FLASH effect” can compound with dosimetric sparing of the proton Bragg peak (BP) using a method called Single Energy Pristine Bragg Peak (SEPBP) FLASH. However, this and other proposed FLASH techniques are constrained by lack of familiar treatment planning systems (TPSs). Creating modules to implement SEPBP FLASH into a commercial TPS opens up the possibility of more widespread investigation of FLASH and lays the groundwork for future clinical translation.

Keywords: flash; implementation novel; novel pencil; treatment planning; bragg peak

Journal Title: Medical Physics
Year Published: 2025

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