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Endocrine Disrupting Chemicals (EDCs) are molecules able to interfere with the vertebrate hormonal system in different ways, a major one being the modification of the activity of nuclear receptors (NRs).… Click to show full abstract
Endocrine Disrupting Chemicals (EDCs) are molecules able to interfere with the vertebrate hormonal system in different ways, a major one being the modification of the activity of nuclear receptors (NRs). Several NRs are expressed in the vertebrate brain during embryonic development and these NRs are suspected to be responsible for the neurodevelopmental defects induced by exposure to EDCs in fishes or amphibians and to participate in several neurodevelopmental disorders observed in humans.
Keywords:
nuclear receptors;
endocrine disrupting;
potential roles;
roles nuclear;
receptors mediating;
disrupting chemicals
Journal Title: Molecular Reproduction and Development
Year Published: 2019
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Journal Title: Molecular Reproduction and Development
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!