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An iterative sparse deconvolution method for simultaneous multicolor 19F‐MRI of multiple contrast agents

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19F‐MRI is gaining widespread interest for cell tracking and quantification of immune and inflammatory cells in vivo. Different fluorinated compounds can be discriminated based on their characteristic MR spectra, allowing… Click to show full abstract

19F‐MRI is gaining widespread interest for cell tracking and quantification of immune and inflammatory cells in vivo. Different fluorinated compounds can be discriminated based on their characteristic MR spectra, allowing in vivo imaging of multiple 19F compounds simultaneously, so‐called multicolor 19F‐MRI. We introduce a method for multicolor 19F‐MRI using an iterative sparse deconvolution method to separate different 19F compounds and remove chemical shift artifacts arising from multiple resonances.

Keywords: multicolor 19f; 19f mri; method; mri; iterative sparse

Journal Title: Magnetic Resonance in Medicine
Year Published: 2019

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