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Improved fetal blood oxygenation and placental estimated measurements of diffusion‐weighted MRI using data‐driven Bayesian modeling

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Motion correction in placental DW‐MRI is challenging due to maternal breathing motion, maternal movements, and rapid intensity changes. Parameter estimates are usually obtained using least‐squares methods for voxel‐wise fitting; however,… Click to show full abstract

Motion correction in placental DW‐MRI is challenging due to maternal breathing motion, maternal movements, and rapid intensity changes. Parameter estimates are usually obtained using least‐squares methods for voxel‐wise fitting; however, they typically give noisy estimates due to low signal‐to‐noise ratio. We introduce a model‐driven registration (MDR) technique which incorporates a placenta‐specific signal model into the registration process, and we present a Bayesian approach for Diffusion‐rElaxation Combined Imaging for Detailed placental Evaluation model to obtain individual and population trends in estimated parameters.

Keywords: improved fetal; fetal blood; diffusion; oxygenation placental; mri; blood oxygenation

Journal Title: Magnetic Resonance in Medicine
Year Published: 2019

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