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Multi‐spin echo T2 relaxation imaging with compressed sensing (METRICS) for rapid myelin water imaging

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Myelin water imaging (MWI) provides a valuable biomarker for myelin, but clinical application has been restricted by long acquisition times. Accelerating the standard multi‐echo T2 acquisition with gradient echoes (GRASE)… Click to show full abstract

Myelin water imaging (MWI) provides a valuable biomarker for myelin, but clinical application has been restricted by long acquisition times. Accelerating the standard multi‐echo T2 acquisition with gradient echoes (GRASE) or by 2D multi‐slice data collection results in image blurring, contrast changes, and other issues. Compressed sensing (CS) can vastly accelerate conventional MRI. In this work, we assessed the use of CS for in vivo human MWI, using a 3D multi spin‐echo sequence.

Keywords: multi spin; compressed sensing; water imaging; spin echo; myelin water

Journal Title: Magnetic Resonance in Medicine
Year Published: 2020

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