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Multi‐echo spin‐echo (MSE) transverse relaxometry mapping using multi‐component models is used to study disease activity in neuromuscular disease by assessing the T2 of the myocytic component (T2water). Current extended phase… Click to show full abstract
Multi‐echo spin‐echo (MSE) transverse relaxometry mapping using multi‐component models is used to study disease activity in neuromuscular disease by assessing the T2 of the myocytic component (T2water). Current extended phase graph algorithms are not optimized for fat fractions above 50% and the effects of inaccuracies in the T2fat calibration remain unexplored. Hence, we aimed to improve the performance of extended phase graph fitting methods over a large range of fat fractions, by including the slice‐selection flip angle profile, a through‐plane chemical‐shift displacement correction, and optimized calibration of T2fat.
Journal Title: Magnetic Resonance in Medicine
Year Published: 2020
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