Acute ischemic stroke induces deoxyhemoglobin accumulation around the ischemic region while activating endothelial nitric oxide synthase (eNOS) coupling and the subsequent release of nitric oxide (NO). Because deoxyhemoglobin is a… Click to show full abstract
Acute ischemic stroke induces deoxyhemoglobin accumulation around the ischemic region while activating endothelial nitric oxide synthase (eNOS) coupling and the subsequent release of nitric oxide (NO). Because deoxyhemoglobin is a natural NO spin trap, its interplay with NO could be prominent during acute stroke. Its interaction with NO has been shown to induce overt paramagnetic signals in vitro; our goal was to investigate whether this interplay can be detected using MRI.
Keywords:
ischemic stroke;
endothelial nitric;
stroke induces;
acute ischemic;
nitric oxide;
stroke
Journal Title: Magnetic Resonance in Medicine
Year Published: 2020
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Journal Title: Magnetic Resonance in Medicine
Year Published: 2020
Link to full text (if available)
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recommendations!