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Quantifying myelin in crossing fibers using diffusion‐prepared phase imaging: Theory and simulations

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Myelin has long been the target of neuroimaging research. However, most available techniques can only provide a voxel‐averaged estimate of myelin content. In the human brain, white matter fiber pathways… Click to show full abstract

Myelin has long been the target of neuroimaging research. However, most available techniques can only provide a voxel‐averaged estimate of myelin content. In the human brain, white matter fiber pathways connecting different brain areas and carrying different functions often cross each other in the same voxel. A measure that can differentiate the degree of myelination of crossing fibers would provide a more specific marker of myelination.

Keywords: myelin crossing; fibers using; quantifying myelin; myelin; using diffusion; crossing fibers

Journal Title: Magnetic Resonance in Medicine
Year Published: 2021

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