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Whole‐brain mapping of mouse CSF flow via HEAP‐METRIC phase‐contrast MRI

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CSF plays important roles in clearing brain waste and homeostasis. However, mapping whole‐brain CSF flow in the rodents is difficult, primarily due to its assumed very low velocity. Therefore, we… Click to show full abstract

CSF plays important roles in clearing brain waste and homeostasis. However, mapping whole‐brain CSF flow in the rodents is difficult, primarily due to its assumed very low velocity. Therefore, we aimed to develop a novel phase‐contrast MRI method to map whole‐brain CSF flow in the mouse brain.

Keywords: csf flow; csf; whole brain; phase contrast; brain

Journal Title: Magnetic Resonance in Medicine
Year Published: 2022

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