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Improved multi‐echo gradient echo myelin water fraction mapping using complex‐valued neural network analysis

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Previously, an artificial neural network method was introduced to estimate quantitative myelin water fraction (MWF) using multi‐echo gradient‐echo data. However, the fiber orientation of white matter with respect to B0… Click to show full abstract

Previously, an artificial neural network method was introduced to estimate quantitative myelin water fraction (MWF) using multi‐echo gradient‐echo data. However, the fiber orientation of white matter with respect to B0 could bias the quantification of MWF. Here, we developed an advanced workflow for MWF estimation that could improve the quantification of MWF.

Keywords: multi echo; neural network; myelin water; water fraction; gradient echo; echo gradient

Journal Title: Magnetic Resonance in Medicine
Year Published: 2022

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