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Blood–brain barrier permeability in response to caffeine challenge

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Caffeine is known to alter brain perfusion by acting as an adenosine antagonist, but its effect on blood–brain barrier (BBB) permeability is not fully elucidated. This study aimed to dynamically… Click to show full abstract

Caffeine is known to alter brain perfusion by acting as an adenosine antagonist, but its effect on blood–brain barrier (BBB) permeability is not fully elucidated. This study aimed to dynamically monitor BBB permeability to water after a single dose of caffeine tablet using a non‐contrast MRI technique.

Keywords: blood brain; brain barrier; brain; caffeine; permeability

Journal Title: Magnetic Resonance in Medicine
Year Published: 2022

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