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Quasi–steady‐state amide proton transfer (QUASS APT) MRI enhances pH‐weighted imaging of acute stroke

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Chemical exchange saturation transfer (CEST) imaging measurement depends not only on the labile proton concentration and pH‐dependent exchange rate but also on experimental conditions, including the relaxation delay and radiofrequency… Click to show full abstract

Chemical exchange saturation transfer (CEST) imaging measurement depends not only on the labile proton concentration and pH‐dependent exchange rate but also on experimental conditions, including the relaxation delay and radiofrequency (RF) saturation time. Our study aimed to extend a quasi–steady‐state (QUASS) solution to a modified multi‐slice CEST MRI sequence and test if it provides enhanced pH imaging after acute stroke.

Keywords: imaging acute; transfer; acute stroke; quasi steady; steady state

Journal Title: Magnetic Resonance in Medicine
Year Published: 2022

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