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Gradual changes in microarchitectural properties of cortex and juxtacortical white matter: Observed by anatomical and diffusion MRI

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Characterization of cerebral cortex is challenged by the complexity and heterogeneity of its cyto‐ and myeloarchitecture. This study evaluates quantitative MRI metrics, measured across two cortical depths and in subcortical… Click to show full abstract

Characterization of cerebral cortex is challenged by the complexity and heterogeneity of its cyto‐ and myeloarchitecture. This study evaluates quantitative MRI metrics, measured across two cortical depths and in subcortical white matter (WM) adjacent to cortex (juxtacortical WM), indicative of myelin content, neurite density, and diffusion microenvironment, for a comprehensive characterization of cortical microarchitecture.

Keywords: diffusion; gradual changes; white matter; cortex juxtacortical; changes microarchitectural

Journal Title: Magnetic Resonance in Medicine
Year Published: 2022

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