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Filter exchange imaging (FEXI) and diffusion time (t)‐dependent diffusion kurtosis imaging (DKI(t)) are both sensitive to water exchange between tissue compartments. The restrictive effects of tissue microstructure, however, introduce bias… Click to show full abstract
Filter exchange imaging (FEXI) and diffusion time (t)‐dependent diffusion kurtosis imaging (DKI(t)) are both sensitive to water exchange between tissue compartments. The restrictive effects of tissue microstructure, however, introduce bias to the exchange rate obtained by these two methods, as their interpretation conventionally rely on the Kärger model of barrier limited exchange between Gaussian compartments. Here, we investigated whether FEXI and DKI(t) can provide comparable exchange rates in ex vivo mouse brains.
Journal Title: Magnetic Resonance in Medicine
Year Published: 2022
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