In contrast to conventional MR, signal‐to‐noise ratio (SNR) is not linearly dependent on field strength in hyperpolarized MR, as polarization is generated outside the MR system. Moreover, field inhomogeneity‐induced artifacts… Click to show full abstract
In contrast to conventional MR, signal‐to‐noise ratio (SNR) is not linearly dependent on field strength in hyperpolarized MR, as polarization is generated outside the MR system. Moreover, field inhomogeneity‐induced artifacts and other practical limitations associated with field strengths ≥$$ \ge $$ 3T are alleviated at lower fields. The potential of hyperpolarized 13$$ {}^{13} $$ C spectroscopy and imaging at 1.5T versus 3T is demonstrated in silico, in vitro, and in vivo for applications on clinical MR systems.
               
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