LAUSR

Multi‐b‐value diffusion‐weighted MRI techniques can simultaneously measure the parenchymal diffusivity, microvascular perfusion, and a third, intermediate diffusion component. This component is related to the interstitial fluid in the brain parenchyma. However, simultaneously estimating three diffusion components from multi‐b‐value data is difficult and has strong dependence on SNR and chosen b‐values. As the number of acquired b‐values is limited due to scanning time, it is important to know which b‐values are most effective to be included. Therefore, this study evaluates an optimized b‐value sampling for interstitial fluid estimation.