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Optimization of MR acoustic radiation force imaging (MR‐ARFI) for human transcranial focused ultrasound

MR acoustic radiation force imaging (MR‐ARFI) is an exceptionally promising technique to non‐invasively confirm targeting accuracy and estimate exposure of low‐intensity transcranial focused ultrasound applications. Implementing MR‐ARFI in the human… Click to show full abstract

MR acoustic radiation force imaging (MR‐ARFI) is an exceptionally promising technique to non‐invasively confirm targeting accuracy and estimate exposure of low‐intensity transcranial focused ultrasound applications. Implementing MR‐ARFI in the human brain has been hindered by (1) sensitivity to subject motion, and (2) insufficient SNR at low (<1.0 MPa) ultrasound pressures. The purpose of this study was to optimize human MR‐ARFI to allow reduced ultrasound exposure while at the same time being robust to bulk and physiological motion.

Keywords: focused ultrasound; force imaging; acoustic radiation; imaging arfi; transcranial focused; radiation force

Journal Title: Magnetic Resonance in Medicine
Year Published: 2025

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