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A novel role for follistatin in hypersensitivity following cystitis

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Previous studies have shown that the activin‐binding protein follistatin reduces inflammation in several mouse models of colitis. To determine whether follistatin also has a beneficial effect following bladder inflammation, we… Click to show full abstract

Previous studies have shown that the activin‐binding protein follistatin reduces inflammation in several mouse models of colitis. To determine whether follistatin also has a beneficial effect following bladder inflammation, we induced cystitis in mice using cyclophosphamide (CYP) and examined the relationship between bladder hypersensitivity and bladder follistatin expression.

Keywords: cystitis; follistatin; novel role; role follistatin; follistatin hypersensitivity

Journal Title: Neurourology and Urodynamics
Year Published: 2017

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