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Polymyxin E was used for treating gram‐negative bacterial infections but not recently for fear of its nephrotoxicity. Silybin has potential to counteract nephrotoxicity; however, few studies have investigated its protective… Click to show full abstract
Polymyxin E was used for treating gram‐negative bacterial infections but not recently for fear of its nephrotoxicity. Silybin has potential to counteract nephrotoxicity; however, few studies have investigated its protective effect on the kidney in an animal model. The purpose of the present study was to assess whether silybin could decrease elevated urine and serum renal biochemical markers induced by polymyxin E in rat kidney.
Keywords:
effect;
protective role;
polymyxin;
possible protective;
silybin;
rat
Journal Title: Neurourology and Urodynamics
Year Published: 2017
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Journal Title: Neurourology and Urodynamics
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!