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Capsaicin‐induced rapid neutrophil leukocyte activation in the rat urinary bladder microcirculatory bed

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This study was initiated to investigate the involvement of neutrophil leukocyte activation in neurogenic inflammation, a process also involved in human urinary pathologies, elicited in the rat urinary bladder by… Click to show full abstract

This study was initiated to investigate the involvement of neutrophil leukocyte activation in neurogenic inflammation, a process also involved in human urinary pathologies, elicited in the rat urinary bladder by the local administration of capsaicin, the archetypal TRPV1 agonist. The contribution of afferent nerves and sensory neuropeptides to leukocyte activation in the urinary bladder microcirculatory bed was examined.

Keywords: leukocyte activation; neutrophil leukocyte; urinary bladder; rat urinary

Journal Title: Neurourology and Urodynamics
Year Published: 2018

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